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Wan Namkung Selected Research

Chloride Channels (Chloride Channel)

9/2022Anticancer effect of verteporfin on non-small cell lung cancer via downregulation of ANO1.
11/2021Cinobufagin Exerts Anticancer Activity in Oral Squamous Cell Carcinoma Cells through Downregulation of ANO1.
7/2021Diethylstilbestrol, a Novel ANO1 Inhibitor, Exerts an Anticancer Effect on Non-Small Cell Lung Cancer via Inhibition of ANO1.
9/2020Novel ANO1 Inhibitor from Mallotus apelta Extract Exerts Anticancer Activity through Downregulation of ANO1.
12/2018Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors.
1/2017Inhibition of ANO1 by luteolin and its cytotoxicity in human prostate cancer PC-3 cells.
1/2016Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2.
10/2015Benzopyrimido-pyrrolo-oxazine-dione (R)-BPO-27 Inhibits CFTR Chloride Channel Gating by Competition with ATP.
1/2015Inhibition of ANO1/TMEM16A Chloride Channel by Idebenone and Its Cytotoxicity to Cancer Cell Lines.
7/2014Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice.
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Wan Namkung Research Topics

Disease

9Cystic Fibrosis (Mucoviscidosis)
01/2016 - 09/2003
8Diarrhea
01/2016 - 04/2007
7Neoplasms (Cancer)
09/2022 - 08/2009
5Pancreatitis
03/2019 - 06/2002
4Inflammation (Inflammations)
10/2021 - 06/2002
4Prostatic Neoplasms (Prostate Cancer)
09/2020 - 01/2017
3Hypertension (High Blood Pressure)
01/2016 - 11/2010
3Polycystic Kidney Diseases (Polycystic Kidney Disease)
10/2015 - 05/2008
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2022 - 07/2021
2Dry Eye Syndromes (Dry Eye Syndrome)
05/2022 - 04/2021
2Squamous Cell Carcinoma of Head and Neck
11/2021 - 09/2020
2Carcinoma (Carcinomatosis)
07/2021 - 12/2018
2Allergic Rhinitis
07/2020 - 09/2017
2Breast Neoplasms (Breast Cancer)
02/2020 - 01/2020
2Adenosquamous Carcinoma
01/2020 - 01/2020
2Asthma (Bronchial Asthma)
11/2019 - 01/2016
2Hearing Loss (Hearing Impairment)
01/2019 - 08/2015
2Pain (Aches)
01/2016 - 01/2011
2Infections
07/2014 - 03/2008
2Lung Diseases (Lung Disease)
08/2010 - 06/2009
1Acoustic Neuroma (Acoustic Neurinoma)
11/2022
1Leukemia
01/2022
1COVID-19
01/2022
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2022
1Immune System Diseases (Immune Disorders)
10/2021
1Lupus Nephritis
07/2020
1Chronic Kidney Failure (Chronic Renal Failure)
07/2020
1Splenomegaly
07/2020
1Glomerulonephritis
07/2020
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
07/2020
1Proteinuria
07/2020
1Rhinorrhea
07/2020
1Sepsis (Septicemia)
01/2020
1Adenocarcinoma
01/2020
1Acute Lung Injury
01/2020
1Lung Injury
01/2020
1Respiratory Hypersensitivity
11/2019
1Hypersensitivity (Allergy)
09/2017
1Metaplasia
08/2015
1Nasal Polyps (Nasal Polyp)
09/2013

Drug/Important Bio-Agent (IBA)

16Chloride Channels (Chloride Channel)IBA
09/2022 - 03/2008
7Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA
04/2021 - 09/2003
5Anoctamin-1IBA
09/2022 - 01/2015
4Proteins (Proteins, Gene)FDA Link
09/2020 - 03/2008
4CeruletideIBA
03/2019 - 10/2002
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2022 - 04/2021
2InterleukinsIBA
05/2022 - 04/2021
2indolizineIBA
01/2022 - 01/2020
2Interleukin-8 (Interleukin 8)IBA
04/2021 - 06/2004
2Interleukin-4 (Interleukin 4)IBA
07/2020 - 09/2017
2LuteolinIBA
07/2020 - 01/2017
2Antineoplastic Agents (Antineoplastics)IBA
02/2020 - 01/2020
2LipopolysaccharidesIBA
01/2020 - 03/2019
2Biological ProductsIBA
01/2020 - 01/2020
2TrypsinIBA
11/2008 - 06/2004
2PAR-2 ReceptorIBA
11/2008 - 06/2004
2Phosphotransferases (Kinase)IBA
11/2008 - 06/2002
2NF-kappa B (NF-kB)IBA
10/2002 - 06/2002
1CateninsIBA
11/2022
1celastrolIBA
11/2022
1Verteporfin (Visudyne)FDA Link
09/2022
1Scopolamine (Hyoscine)FDA Link
05/2022
1Interleukin-6 (Interleukin 6)IBA
05/2022
1InterferonsIBA
05/2022
1ThrombinFDA Link
01/2022
1Phospholipid Transfer ProteinsIBA
01/2022
1PhosphatidylserinesIBA
01/2022
1cinobufaginIBA
11/2021
1licochalcone AIBA
10/2021
1Pharmaceutical PreparationsIBA
07/2021
1Diethylstilbestrol (Stilbestrol)FDA Link
07/2021
1Ion Channels (Ion Channel)IBA
04/2021
13-methylquercetinIBA
04/2021
1punicalaginIBA
07/2020
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
07/2020
1Peptide Hydrolases (Proteases)FDA Link
07/2020
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
07/2020
1ElectrolytesIBA
07/2020
1Histamine Receptors (Histamine Receptor)IBA
07/2020
1PyrazinesIBA
02/2020
1Capecitabine (Xeloda)FDA Link
01/2020
1quinone (benzoquinone)IBA
01/2020
1YS-01IBA
01/2020
1MucinsIBA
11/2019
1QuercetinIBA
03/2019
1PotassiumIBA
01/2019
1Histamine (Histamine Dihydrochloride)FDA Link
09/2017
1Carboxylic AcidsIBA
10/2015
1AnionsIBA
08/2015
1Interleukin-13IBA
08/2015
1idebenoneIBA
01/2015
16- t- butyl- 2- (furan- 2- carboxamido)- 4,5,6,7- tetrahydrobenzo(b)thiophene- 3- carboxylic acidIBA
07/2014
1Cholera ToxinIBA
07/2014
1ColforsinIBA
09/2013
1ChloridesIBA
08/2010
1proanthocyanidinIBA
01/2010
1crofelemer (SP-303)IBA
01/2010

Therapy/Procedure

4Drug Therapy (Chemotherapy)
01/2016 - 01/2011
3Therapeutics
07/2020 - 05/2008
1Oral Administration
07/2014